Same-day dispatch on orders by 2 PM ETFree shipping over $150Save up to 50% with volume pricing
0
  1. Home
  2. Shop
  3. Metabolic
  4. 5-Amino-1MQ

Metabolic · Small-molecule NNMT inhibitor (5-amino-1-methylquinolinium)

5-Amino-1MQ

50 mg to 100 mg · Small molecule · 158.19 Da

$85.00per vial

Size$1.70/mg

Size

Quantity10+ of one compound: 40% off

Choose a quantity
1

Same-day dispatch on orders by 2 PM ET, Monday to Friday

Arrives in 2 business days, tracked

Free shipping over $150

Earn Research Credit on top of your discount. VIP earns 3x more.
  • 7 tests, every lotIndependent lab
  • 2 Day ShippingFrom the USA, tracked
  • Encrypted checkoutSSL secured
  • PassedSterility & endotoxin
  • PassedIdentity & purity, 99.85%

For in-vitro research use only. Not for human or animal use.

Researchers also add

01Verified test results

Every lot, independently tested.

5-Amino-1MQ lot SA-5AM-2610 was tested Oct 8, 2026 at an independent laboratory before it shipped. Every value is printed against its limit, so a pass means something.

Independent labIndependent third-party laboratorySample data

Certificate of analysis

99.85%

Purity by HPLC

Profile drawn from the reported purity

Lot
SA-5AM-2610
Tested
Oct 8, 2026
Labelled
50 mg
Measured
50.62 mg
7 of 7 within limitsQR on every label
Full release panel7 passed · 0 flagged
  • PurityHPLC · limit ≥ 99.0%99.85%Pass
  • IdentityMass spectrometry · limit 158.2 ± 1.0 Da158.5 DaPass
  • Net contentQuantitative HPLC · limit ≥ 50 mg50.62 mgPass
  • EndotoxinLAL assay · limit ≤ 0.5 EU/mg0.11 EU/mgPass
  • SterilityMembrane filtration · limit No growthNo growthPass
  • Heavy metalsICP-MS · limit ≤ 10 ppm total1.1 ppmPass
  • MoistureKarl Fischer · limit ≤ 8.0%4.0%Pass

Purity by HPLC, identity by mass spectrometry, net content by quantitative HPLC, endotoxin by LAL, sterility by membrane filtration, heavy metals by ICP-MS and moisture by Karl Fischer. Report SA-5AM-2610-01, Oct 8, 2026. Open the lot record.

Every lot on record

Open any lot's certificate. Your order ships from the current released lot, and its QR code opens this record.

All 2 5-Amino-1MQ lots
Latest
5-Amino-1MQ 50 mgLot SA-5AM-2610

99.85%

HPLC purity

Labelled50 mgMeasured50.62 mg+1.2%
  • IdentityConfirmed
  • EndotoxinPass
  • SterilityNo growth
  • Heavy metalsPass

Tested Oct 8, 2026 · 7/7 assays · sample

5-Amino-1MQ 50 mgLot SA-5AM-2609

99.61%

HPLC purity

Labelled50 mgMeasured50.98 mg+2.0%
  • IdentityConfirmed
  • EndotoxinPass
  • SterilityNo growth
  • Heavy metalsPass

Tested Sep 10, 2026 · 7/7 assays · sample

02Verify your vial

Three steps from label to lab.

  1. 01Scan the label

    Every vial label carries a QR code. Point your phone camera at it.

  2. 02Land on its record

    The code opens that lot's certificate with every assay value. No phone? Type the lot from your packing slip on Verify a lot.

  3. 03Check it with the lab

    Each signed certificate links to the lab's own verification page, so the report can be confirmed independently of us.

03Analytical identity

5-Amino-1MQ, molecule by molecule.

Studied in metabolic receptor-signalling models in vitro.

CompoundSmall-molecule NNMT inhibitor (5-amino-1-methylquinolinium)
FormulaC10H10N2
Molecular weight158.19 Da
TypeSmall molecule
CAS4213-45-0
FormPowder, 50 mg, 100 mg
StorageSealed at -20 °C, away from light and moisture

Structure

A small molecule, not a peptide chain. Its structure is confirmed by mass spectrometry on every lot certificate.

04In the lab

How 5-Amino-1MQ is studied to work.

5-Amino-1MQ is a small-molecule inhibitor of NNMT, the enzyme that methylates nicotinamide. In laboratory research it lowered the NNMT product 1-MNA and raised NAD+ and SAM in adipocytes, and supported aged muscle stem cell activity.

Compound

5-Amino-1MQNNMT inhibitor, 5-amino-1-methylquinolinium
  1. Adipocyte metabolism

    Cultured adipocytes

    • NNMT
    • 1-MNA
    • NAD+ and SAM

    Endpoint studied

    Lower lipogenesis

    NNMT inhibitors cut intracellular 1-MNA, raised NAD+ and SAM, and suppressed lipogenesis.

    Neelakantan 2018 · PMID 29155147
  2. Muscle stem cells

    Muscle stem cells, myoblasts

    • NNMT
    • NAD+/NADH

    Endpoint studied

    Myofiber regeneration

    Stem cells proliferated and fused more after injury; myoblasts differentiated more, with NAD+/NADH shifts.

    Neelakantan 2019 · PMID 30753815

Pathways as reported in the cited laboratory studies. For in-vitro research use only.

05Research history

7 years in the literature.

5 milestones, each linked to its PubMed record

  1. 2017

    Journal of Medicinal Chemistry

    Quinolinium NNMT inhibitors

    A structure-activity study identifies methylquinoliniums as NNMT inhibitors near 1 micromolar; docking places them in the nicotinamide site.

    PubMed · PMID 28548833
  2. 2018

    Biochemical Pharmacology

    Selective, cell-permeable

    Methylquinolinium inhibitors cross membranes, spare related methyltransferases, and raise NAD+ and SAM in cultured adipocytes.

    PubMed · PMID 29155147
  3. 2019

    Biochemical Pharmacology

    Aged muscle stem cells

    In an aged muscle injury model, stem cell activity rose, giving larger myofibers and about 70% higher contractile torque.

    PubMed · PMID 30753815
  4. 2021

    Journal of Pharmaceutical and Biomedical Analysis

    A validated plasma assay

    An LC-MS/MS assay is validated to measure 5-amino-1MQ in plasma and urine samples.

    PubMed · PMID 34304009
  5. 2024

    Diabetes, Obesity & Metabolism

    Liver and glucose markers

    In an obesity model, 5A1MQ improved glucose tolerance and insulin sensitivity, eased hepatic steatosis, and reached adipose, muscle and liver.

    PubMed · PMID 39161060 Latest

Laboratory research only, cited for research context. Not a claim about use in people.

06Questions

Frequently asked questions.

About 5-Amino-1MQ, its certificate and your order.

Need assistance? We’re here to help.

Email [email protected], Monday to Friday. A person replies within one business day.

01Which lot will I receive?

The current released lot, SA-5AM-2610. Scan the QR code on the vial label to open its certificate. The lot number is also on your packing slip, and the full certificate is here.

02Is the certificate real, and can I check it?

Every certificate is issued by an independent laboratory. Each lot has its own public record page with every assay value, and a link to verify the report on the lab's own site once the signed PDF is posted.

03Why does net content show more than 50 mg?

Vials are filled slightly over the labelled mass so that every vial meets it. Net content is measured on each lot and published as a number, not a pass.

04What if the vial arrives without vacuum or damaged?

Email [email protected] within 7 days with your order number and a photo and we will replace it.

05When will it ship?

Orders by 2 PM ET on a weekday ship the same day, with tracking emailed when the label prints.

06Is 5-Amino-1MQ for human use?

No. It is sold strictly for in-vitro laboratory research and is not for human or animal use of any kind.

07Complete the box

Every vial counts toward your price.

3+ vials 25% off and 5+ vials 30% off across any mix, 10+ of one compound 40% off, 50+ of one compound 50% off.

Build a box
5-Amino-1MQ50 mg · $85.00
1

View

Certificate

Loading certificate