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Metabolic · GLP-1 receptor agonist peptide

GLP-1 S

20 mg · 31 residues · 4113.58 Da

$85.00per vial

Size$4.25/mg

20 mg Lyophilised · sealed vial

Quantity10+ of one compound: 40% off

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  • 7 tests, every lotIndependent lab
  • 2 Day ShippingFrom the USA, tracked
  • Encrypted checkoutSSL secured
  • PassedSterility & endotoxin
  • PassedIdentity & purity, 99.17%

For in-vitro research use only. Not for human or animal use.

Researchers also add

01Verified test results

Every lot, independently tested.

GLP-1 S lot SA-G1S-2610 was tested Oct 8, 2026 at an independent laboratory before it shipped. Every value is printed against its limit, so a pass means something.

Independent labIndependent third-party laboratorySample data

Certificate of analysis

99.17%

Purity by HPLC

Profile drawn from the reported purity

Lot
SA-G1S-2610
Tested
Oct 8, 2026
Labelled
20 mg
Measured
20.41 mg
7 of 7 within limitsQR on every label
Full release panel7 passed · 0 flagged
  • PurityHPLC · limit ≥ 99.0%99.17%Pass
  • IdentityMass spectrometry · limit 4113.6 ± 1.0 Da4113.8 DaPass
  • Net contentQuantitative HPLC · limit ≥ 20 mg20.41 mgPass
  • EndotoxinLAL assay · limit ≤ 0.5 EU/mg0.11 EU/mgPass
  • SterilityMembrane filtration · limit No growthNo growthPass
  • Heavy metalsICP-MS · limit ≤ 10 ppm total0.4 ppmPass
  • MoistureKarl Fischer · limit ≤ 8.0%2.8%Pass

Purity by HPLC, identity by mass spectrometry, net content by quantitative HPLC, endotoxin by LAL, sterility by membrane filtration, heavy metals by ICP-MS and moisture by Karl Fischer. Report SA-G1S-2610-01, Oct 8, 2026. Open the lot record.

Every lot on record

Open any lot's certificate. Your order ships from the current released lot, and its QR code opens this record.

All 2 GLP-1 S lots
Latest
GLP-1 S 20 mgLot SA-G1S-2610

99.17%

HPLC purity

Labelled20 mgMeasured20.41 mg+2.0%
  • IdentityConfirmed
  • EndotoxinPass
  • SterilityNo growth
  • Heavy metalsPass

Tested Oct 8, 2026 · 7/7 assays · sample

GLP-1 S 20 mgLot SA-G1S-2609

99.44%

HPLC purity

Labelled20 mgMeasured20.35 mg+1.8%
  • IdentityConfirmed
  • EndotoxinPass
  • SterilityNo growth
  • Heavy metalsPass

Tested Sep 10, 2026 · 7/7 assays · sample

02Verify your vial

Three steps from label to lab.

  1. 01Scan the label

    Every vial label carries a QR code. Point your phone camera at it.

  2. 02Land on its record

    The code opens that lot's certificate with every assay value. No phone? Type the lot from your packing slip on Verify a lot.

  3. 03Check it with the lab

    Each signed certificate links to the lab's own verification page, so the report can be confirmed independently of us.

03Analytical identity

GLP-1 S, molecule by molecule.

Studied in incretin receptor-signalling models in vitro.

CompoundGLP-1 receptor agonist peptide
FormulaC187H291N45O59
Molecular weight4113.58 Da
Residues31
CAS910463-68-2
FormLyophilised powder, 20 mg
StorageSealed at -20 °C, away from light and moisture

Sequence

31-residue chain. The full sequence and its mass-spec confirmation are on each lot certificate.

04In the lab

How GLP-1 S is studied to work.

GLP-1 S is a GLP-1 receptor agonist whose fatty acid chain binds albumin, giving a long half-life with nanomolar GLP-1R affinity in lab studies. Cryo-EM shows it contacts the receptor like native GLP-1, and it reaches brain GLP-1R sites near the ventricles.

Compound

GLP-1 SC-18 diacid-acylated Aib8 GLP-1 analog
  1. Albumin binding

    Receptor and albumin assays

    • Fatty acid
    • Albumin
    • GLP-1R

    Endpoint studied

    Long plasma half-life

    GLP-1R affinity of 0.38 nM, higher albumin affinity, and a 46-hour plasma half-life in a laboratory model.

    Lau 2015 · PMID 26308095
  2. Receptor structure

    GLP-1R-Gs complexes

    • GLP-1R
    • Gs protein

    Endpoint studied

    Active receptor complex

    Cryo-EM structures: peptide contacts like native GLP-1, with different receptor and peptide motions.

    Zhang 2021 · PMID 34260945
  3. Brain access

    Brainstem and hypothalamus

    • GLP-1R
    • c-Fos

    Endpoint studied

    Brain area activation

    Entered via circumventricular organs, not across the blood-brain barrier; c-Fos rose in 10 brain areas.

    Gabery 2020 · PMID 32213703

Pathways as reported in the cited laboratory studies. For in-vitro research use only.

05Research history

6 years in the literature.

5 milestones, each linked to its PubMed record

  1. 2015

    Journal of Medicinal Chemistry

    Designed for long action

    Fatty acid and linker chemistry were tuned for high albumin affinity and GLP-1R potency, with Aib8 and Arg34 substitutions.

    PubMed · PMID 26308095
  2. 2018

    JACC. Basic to Translational Science

    Plaque in vessel models

    Plaque development fell in two atherosclerosis models, and diet-driven inflammatory gene changes in aortic tissue reversed.

    PubMed · PMID 30623143
  3. 2019

    Frontiers in Endocrinology

    Design history reviewed

    A review of how fatty acid and linker choices were optimized for albumin binding while keeping GLP-1R potency.

    PubMed · PMID 31031702
  4. 2020

    JCI Insight

    Mapping brain access

    It reached the brainstem, septal nucleus and hypothalamus via circumventricular organs and raised c-Fos in 10 brain areas.

    PubMed · PMID 32213703
  5. 2021

    Cell Reports

    Cryo-EM receptor structure

    Cryo-EM structures of the GLP-1R-Gs complex show peptide contacts similar to native GLP-1.

    PubMed · PMID 34260945 Latest

Laboratory research only, cited for research context. Not a claim about use in people.

06Questions

Frequently asked questions.

About GLP-1 S, its certificate and your order.

Need assistance? We’re here to help.

Email [email protected], Monday to Friday. A person replies within one business day.

01Which lot will I receive?

The current released lot, SA-G1S-2610. Scan the QR code on the vial label to open its certificate. The lot number is also on your packing slip, and the full certificate is here.

02Is the certificate real, and can I check it?

Every certificate is issued by an independent laboratory. Each lot has its own public record page with every assay value, and a link to verify the report on the lab's own site once the signed PDF is posted.

03Why does net content show more than 20 mg?

Vials are filled slightly over the labelled mass so that every vial meets it. Net content is measured on each lot and published as a number, not a pass.

04What if the vial arrives without vacuum or damaged?

Email [email protected] within 7 days with your order number and a photo and we will replace it.

05When will it ship?

Orders by 2 PM ET on a weekday ship the same day, with tracking emailed when the label prints.

06Is GLP-1 S for human use?

No. It is sold strictly for in-vitro laboratory research and is not for human or animal use of any kind.

07Complete the box

Every vial counts toward your price.

3+ vials 25% off and 5+ vials 30% off across any mix, 10+ of one compound 40% off, 50+ of one compound 50% off.

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GLP-1 S20 mg · $85.00
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