| Test | Method | Limit | Result |
|---|---|---|---|
| Purity | HPLC | ≥ 99.0% | 99.35% |
| Identity | Mass spectrometry | 813.9 ± 1.0 Da | 813.9 Da |
| Net content | Quantitative HPLC | ≥ 10 mg | 10.18 mg |
| Endotoxin | LAL assay | ≤ 0.5 EU/mg | 0.09 EU/mg |
| Sterility | Membrane filtration | No growth | No growth |
| Heavy metals | ICP-MS | ≤ 10 ppm total | 0.5 ppm |
| Moisture | Karl Fischer | ≤ 8.0% | 3.7% |
Synthetic heptapeptide, ACTH(4-10) analog
C37H51N9O10S
813.93 Da · 7 residues
Neural · Synthetic heptapeptide, ACTH(4-10) analog
10 mg · 7 residues · 813.93 Da
Size$6.00/mg
Quantity10+ of one compound: 40% off
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For in-vitro research use only. Not for human or animal use.
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GLP-2 TZ 10 mg01Verified test results
Semax lot SA-SMX-2611 was tested Oct 12, 2026 at an independent laboratory before it shipped. Every value is printed against its limit, so a pass means something.
Certificate of analysis
99.35%
Purity by HPLC
Profile drawn from the reported purity
Purity by HPLC, identity by mass spectrometry, net content by quantitative HPLC, endotoxin by LAL, sterility by membrane filtration, heavy metals by ICP-MS and moisture by Karl Fischer. Report SA-SMX-2611-01, Oct 12, 2026. Open the lot record.
Open any lot's certificate. Your order ships from the current released lot, and its QR code opens this record.
99.35%
HPLC purity
Tested Oct 12, 2026 · 7/7 assays · sample
99.18%
HPLC purity
Tested Sep 4, 2026 · 7/7 assays · sample
02Verify your vial
Every vial label carries a QR code. Point your phone camera at it.
The code opens that lot's certificate with every assay value. No phone? Type the lot from your packing slip on Verify a lot.
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03Analytical identity
Studied in neuropeptide-signalling models in vitro.
| Compound | Synthetic heptapeptide, ACTH(4-10) analog |
|---|---|
| Formula | C37H51N9O10S |
| Molecular weight | 813.93 Da |
| Residues | 7 |
| Form | Lyophilised powder, 10 mg |
| Storage | Sealed at -20 °C, away from light and moisture |
Sequence
Side-chain composition
Every heavy atom is placed from the sequence with ideal bond lengths and angles, so the connectivity is exact. The pose is idealised (an extended chain) and is not a measured conformation. Identity for each lot is confirmed on its certificate.
Structure viewer04In the lab
Semax binds specific, calcium-dependent sites in basal forebrain membranes, but no receptor has been confirmed. In laboratory research it raises BDNF and TrkB activity in brain tissue and binds copper(II).
Compound
SemaxSynthetic ACTH(4-10) analog, Met-Glu-His-Phe-Pro-Gly-ProBasal forebrain
Endpoint studied
Labeled Semax bound specifically and reversibly (KD 2.4 nM); BDNF protein rose in basal forebrain at 3 h.
Dolotov 2006 · PMID 16635254Hippocampal tissue
Endpoint studied
BDNF protein rose 1.4-fold and TrkB tyrosine phosphorylation 1.6-fold; BDNF exon III mRNA rose 3-fold.
Dolotov 2006 · PMID 16996037Pathways as reported in the cited laboratory studies. For in-vitro research use only.
05Research history
4 milestones, each linked to its PubMed record
Biochemical and Biophysical Research Communications
Serum breakdown of ACTH(4-10) and Semax is mapped; aminopeptidases trim both, but Semax is more stable against the other enzymes.
PubMed · PMID 1851003Neuroscience Letters
In basal forebrain glial cultures, BDNF mRNA rose eight-fold and NGF mRNA five-fold 30 minutes after Semax.
PubMed · PMID 11457573Journal of Neurochemistry
Tritium-labeled Semax binds basal forebrain membranes with nanomolar affinity, and BDNF protein rises there within 3 hours.
PubMed · PMID 16635254Journal of Inorganic Biochemistry
Semax binds copper(II) in a 4N planar mode and lowers copper-induced toxicity in SH-SY5Y and RBE4 cell lines.
PubMed · PMID 25310602 LatestLaboratory research only, cited for research context. Not a claim about use in people.
06Questions
About Semax, its certificate and your order.
Email [email protected], Monday to Friday. A person replies within one business day.
The current released lot, SA-SMX-2611. Scan the QR code on the vial label to open its certificate. The lot number is also on your packing slip, and the full certificate is here.
Every certificate is issued by an independent laboratory. Each lot has its own public record page with every assay value, and a link to verify the report on the lab's own site once the signed PDF is posted.
Vials are filled slightly over the labelled mass so that every vial meets it. Net content is measured on each lot and published as a number, not a pass.
Email [email protected] within 7 days with your order number and a photo and we will replace it.
Orders by 2 PM ET on a weekday ship the same day, with tracking emailed when the label prints.
No. It is sold strictly for in-vitro laboratory research and is not for human or animal use of any kind.
07Complete the box
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