Certificate of analysis
99.47%
Purity by HPLC
Profile drawn from the reported purity
- Lot
- SA-TA1-2610
- Tested
- Oct 8, 2026
- Labelled
- 10 mg
- Measured
- 10.16 mg

| Test | Method | Limit | Result |
|---|---|---|---|
| Purity | HPLC | ≥ 99.0% | 99.47% |
| Identity | Mass spectrometry | 3108.3 ± 1.0 Da | 3108.4 Da |
| Net content | Quantitative HPLC | ≥ 10 mg | 10.16 mg |
| Endotoxin | LAL assay | ≤ 0.5 EU/mg | 0.10 EU/mg |
| Sterility | Membrane filtration | No growth | No growth |
| Heavy metals | ICP-MS | ≤ 10 ppm total | 0.8 ppm |
| Moisture | Karl Fischer | ≤ 8.0% | 4.1% |
Acetylated 28-residue thymic peptide
C129H215N33O55
3108.3 Da · 28 residues
28-residue chain. The full sequence and its mass-spec confirmation are on each lot certificate.
Tissue + immune · Acetylated 28-residue thymic peptide
10 mg · 28 residues · 3108.3 Da
Size$9.50/mg
Quantity10+ of one compound: 40% off
Same-day dispatch on orders by 2 PM ET, Monday to Friday
Arrives in 2 business days, tracked
Free shipping over $150
For in-vitro research use only. Not for human or animal use.
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GLP-3 RT 5 mg01Verified test results
Thymosin Alpha-1 lot SA-TA1-2610 was tested Oct 8, 2026 at an independent laboratory before it shipped. Every value is printed against its limit, so a pass means something.
Certificate of analysis
99.47%
Purity by HPLC
Profile drawn from the reported purity
Purity by HPLC, identity by mass spectrometry, net content by quantitative HPLC, endotoxin by LAL, sterility by membrane filtration, heavy metals by ICP-MS and moisture by Karl Fischer. Report SA-TA1-2610-01, Oct 8, 2026. Open the lot record.
Open any lot's certificate. Your order ships from the current released lot, and its QR code opens this record.

99.47%
HPLC purity
Tested Oct 8, 2026 · 7/7 assays · sample

99.49%
HPLC purity
Tested Sep 10, 2026 · 7/7 assays · sample
02Verify your vial
Every vial label carries a QR code. Point your phone camera at it.
The code opens that lot's certificate with every assay value. No phone? Type the lot from your packing slip on Verify a lot.
Each signed certificate links to the lab's own verification page, so the report can be confirmed independently of us.
03Analytical identity
Studied in immune-signalling models in vitro.
| Compound | Acetylated 28-residue thymic peptide |
|---|---|
| Formula | C129H215N33O55 |
| Molecular weight | 3108.3 Da |
| Residues | 28 |
| CAS | 62304-98-7 |
| Form | Lyophilised powder, 10 mg |
| Storage | Sealed at -20 °C, away from light and moisture |
Sequence
28-residue chain. The full sequence and its mass-spec confirmation are on each lot certificate.
Every heavy atom is placed from the sequence with ideal bond lengths and angles, so the connectivity is exact. The pose is idealised (an ideal helix) and is not a measured conformation. Identity for each lot is confirmed on its certificate.
Structure viewer04In the lab
Thymosin alpha-1 is a 28-amino-acid peptide first isolated from thymus tissue. In laboratory research it signals through Toll-like receptor pathways (MyD88, TRAF6, NF-kB) in dendritic cells and macrophages and induces the IDO enzyme in dendritic cells.

Compound
Thymosin Alpha-128-amino-acid peptide first isolated from the thymusDendritic cells
Endpoint studied
Dendritic cells matured and made IL-12 through MyD88-dependent Toll-like receptor and p38/NF-kB signaling.
Romani 2004 · PMID 14982877Macrophages, fibroblasts
Endpoint studied
IL-6 induction needed IKKbeta and TRAF6; a TRAF6, p62, PKC iota/zeta and IKK signalsome formed.
Zhang 2005 · PMID 15905851Dendritic cells
Endpoint studied
IDO expression and activity rose, needing TLR9 and type I interferon receptor signals; IL-10 followed.
Romani 2006 · PMID 16741252Pathways as reported in the cited laboratory studies. For in-vitro research use only.
05Research history
5 milestones, each linked to its PubMed record
Proceedings of the National Academy of Sciences of the United States of America
A heat-stable, acidic 28-residue polypeptide from thymus is isolated, sequenced and named thymosin alpha 1.
PubMed · PMID 265536Biochemistry
Thymosin alpha 1 is made by solid-phase synthesis with improved yield, and the synthetic peptide is active in a rosette assay.
PubMed · PMID 7190831Blood
In dendritic cells it drives maturation and IL-12 through MyD88-dependent Toll-like receptor and p38/NF-kB signaling.
PubMed · PMID 14982877EMBO Reports
IL-6 induction runs through TRAF6, IKK and NF-kB, with a signalsome of TRAF6, p62, PKC iota/zeta and IKK.
PubMed · PMID 15905851Annals of the New York Academy of Sciences
A review summarizes its action on dendritic cells: TLR/MyD88 signaling, TLR9 viral sensing with IRF7, and IDO induction.
PubMed · PMID 17495242 LatestLaboratory research only, cited for research context. Not a claim about use in people.
06Questions
About Thymosin Alpha-1, its certificate and your order.
Email [email protected], Monday to Friday. A person replies within one business day.
The current released lot, SA-TA1-2610. Scan the QR code on the vial label to open its certificate. The lot number is also on your packing slip, and the full certificate is here.
Every certificate is issued by an independent laboratory. Each lot has its own public record page with every assay value, and a link to verify the report on the lab's own site once the signed PDF is posted.
Vials are filled slightly over the labelled mass so that every vial meets it. Net content is measured on each lot and published as a number, not a pass.
Email [email protected] within 7 days with your order number and a photo and we will replace it.
Orders by 2 PM ET on a weekday ship the same day, with tracking emailed when the label prints.
No. It is sold strictly for in-vitro laboratory research and is not for human or animal use of any kind.
07Complete the box
3+ vials 25% off and 5+ vials 30% off across any mix, 10+ of one compound 40% off, 50+ of one compound 50% off.

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