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Tissue + immune · Acetylated 28-residue thymic peptide

Thymosin Alpha-1

10 mg · 28 residues · 3108.3 Da

$95.00per vial

Size$9.50/mg

10 mg Lyophilised · sealed vial

Quantity10+ of one compound: 40% off

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  • 7 tests, every lotIndependent lab
  • 2 Day ShippingFrom the USA, tracked
  • Encrypted checkoutSSL secured
  • PassedSterility & endotoxin
  • PassedIdentity & purity, 99.47%

For in-vitro research use only. Not for human or animal use.

Researchers also add

01Verified test results

Every lot, independently tested.

Thymosin Alpha-1 lot SA-TA1-2610 was tested Oct 8, 2026 at an independent laboratory before it shipped. Every value is printed against its limit, so a pass means something.

Independent labIndependent third-party laboratorySample data

Certificate of analysis

99.47%

Purity by HPLC

Profile drawn from the reported purity

Lot
SA-TA1-2610
Tested
Oct 8, 2026
Labelled
10 mg
Measured
10.16 mg
7 of 7 within limitsQR on every label
Full release panel7 passed · 0 flagged
  • PurityHPLC · limit ≥ 99.0%99.47%Pass
  • IdentityMass spectrometry · limit 3108.3 ± 1.0 Da3108.4 DaPass
  • Net contentQuantitative HPLC · limit ≥ 10 mg10.16 mgPass
  • EndotoxinLAL assay · limit ≤ 0.5 EU/mg0.10 EU/mgPass
  • SterilityMembrane filtration · limit No growthNo growthPass
  • Heavy metalsICP-MS · limit ≤ 10 ppm total0.8 ppmPass
  • MoistureKarl Fischer · limit ≤ 8.0%4.1%Pass

Purity by HPLC, identity by mass spectrometry, net content by quantitative HPLC, endotoxin by LAL, sterility by membrane filtration, heavy metals by ICP-MS and moisture by Karl Fischer. Report SA-TA1-2610-01, Oct 8, 2026. Open the lot record.

Every lot on record

Open any lot's certificate. Your order ships from the current released lot, and its QR code opens this record.

All 2 Thymosin Alpha-1 lots
Latest
Thymosin Alpha-1 10 mgLot SA-TA1-2610

99.47%

HPLC purity

Labelled10 mgMeasured10.16 mg+1.6%
  • IdentityConfirmed
  • EndotoxinPass
  • SterilityNo growth
  • Heavy metalsPass

Tested Oct 8, 2026 · 7/7 assays · sample

Thymosin Alpha-1 10 mgLot SA-TA1-2609

99.49%

HPLC purity

Labelled10 mgMeasured10.27 mg+2.7%
  • IdentityConfirmed
  • EndotoxinPass
  • SterilityNo growth
  • Heavy metalsPass

Tested Sep 10, 2026 · 7/7 assays · sample

02Verify your vial

Three steps from label to lab.

  1. 01Scan the label

    Every vial label carries a QR code. Point your phone camera at it.

  2. 02Land on its record

    The code opens that lot's certificate with every assay value. No phone? Type the lot from your packing slip on Verify a lot.

  3. 03Check it with the lab

    Each signed certificate links to the lab's own verification page, so the report can be confirmed independently of us.

03Analytical identity

Thymosin Alpha-1, molecule by molecule.

Studied in immune-signalling models in vitro.

CompoundAcetylated 28-residue thymic peptide
FormulaC129H215N33O55
Molecular weight3108.3 Da
Residues28
CAS62304-98-7
FormLyophilised powder, 10 mg
StorageSealed at -20 °C, away from light and moisture

Sequence

28-residue chain. The full sequence and its mass-spec confirmation are on each lot certificate.

C129H215N33O553108.3 Da
Drag to turn
Residues · hover to locate28 residues
Heavy atoms
217
Bonds
216
Composition
C129 N33 O55
Rings
0
Metal centre
None
Chain length
28 residues

Every heavy atom is placed from the sequence with ideal bond lengths and angles, so the connectivity is exact. The pose is idealised (an ideal helix) and is not a measured conformation. Identity for each lot is confirmed on its certificate.

Structure viewer

04In the lab

How Thymosin Alpha-1 is studied to work.

Thymosin alpha-1 is a 28-amino-acid peptide first isolated from thymus tissue. In laboratory research it signals through Toll-like receptor pathways (MyD88, TRAF6, NF-kB) in dendritic cells and macrophages and induces the IDO enzyme in dendritic cells.

Compound

Thymosin Alpha-128-amino-acid peptide first isolated from the thymus
  1. Dendritic cells

    Dendritic cells

    • TLRs
    • MyD88
    • p38 MAPK
    • NF-kB

    Endpoint studied

    Maturation and IL-12

    Dendritic cells matured and made IL-12 through MyD88-dependent Toll-like receptor and p38/NF-kB signaling.

    Romani 2004 · PMID 14982877
  2. IL-6 induction

    Macrophages, fibroblasts

    • TRAF6
    • IKK
    • NF-kB

    Endpoint studied

    IL-6 expression

    IL-6 induction needed IKKbeta and TRAF6; a TRAF6, p62, PKC iota/zeta and IKK signalsome formed.

    Zhang 2005 · PMID 15905851
  3. Tolerance signaling

    Dendritic cells

    • TLR9
    • IDO

    Endpoint studied

    IL-10, regulatory T cells

    IDO expression and activity rose, needing TLR9 and type I interferon receptor signals; IL-10 followed.

    Romani 2006 · PMID 16741252

Pathways as reported in the cited laboratory studies. For in-vitro research use only.

05Research history

30 years in the literature.

5 milestones, each linked to its PubMed record

  1. 1977

    Proceedings of the National Academy of Sciences of the United States of America

    Isolated and sequenced

    A heat-stable, acidic 28-residue polypeptide from thymus is isolated, sequenced and named thymosin alpha 1.

    PubMed · PMID 265536
  2. 1980

    Biochemistry

    Solid-phase synthesis

    Thymosin alpha 1 is made by solid-phase synthesis with improved yield, and the synthetic peptide is active in a rosette assay.

    PubMed · PMID 7190831
  3. 2004

    Blood

    Toll-like receptor signaling

    In dendritic cells it drives maturation and IL-12 through MyD88-dependent Toll-like receptor and p38/NF-kB signaling.

    PubMed · PMID 14982877
  4. 2005

    EMBO Reports

    TRAF6 to IKK

    IL-6 induction runs through TRAF6, IKK and NF-kB, with a signalsome of TRAF6, p62, PKC iota/zeta and IKK.

    PubMed · PMID 15905851
  5. 2007

    Annals of the New York Academy of Sciences

    Dendritic cell review

    A review summarizes its action on dendritic cells: TLR/MyD88 signaling, TLR9 viral sensing with IRF7, and IDO induction.

    PubMed · PMID 17495242 Latest

Laboratory research only, cited for research context. Not a claim about use in people.

06Questions

Frequently asked questions.

About Thymosin Alpha-1, its certificate and your order.

Need assistance? We’re here to help.

Email [email protected], Monday to Friday. A person replies within one business day.

01Which lot will I receive?

The current released lot, SA-TA1-2610. Scan the QR code on the vial label to open its certificate. The lot number is also on your packing slip, and the full certificate is here.

02Is the certificate real, and can I check it?

Every certificate is issued by an independent laboratory. Each lot has its own public record page with every assay value, and a link to verify the report on the lab's own site once the signed PDF is posted.

03Why does net content show more than 10 mg?

Vials are filled slightly over the labelled mass so that every vial meets it. Net content is measured on each lot and published as a number, not a pass.

04What if the vial arrives without vacuum or damaged?

Email [email protected] within 7 days with your order number and a photo and we will replace it.

05When will it ship?

Orders by 2 PM ET on a weekday ship the same day, with tracking emailed when the label prints.

06Is Thymosin Alpha-1 for human use?

No. It is sold strictly for in-vitro laboratory research and is not for human or animal use of any kind.

07Complete the box

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Thymosin Alpha-110 mg · $95.00
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