Certificate of analysis
99.40%
Purity by HPLC
Profile drawn from the reported purity
- Lot
- SA-IGF-2610
- Tested
- Oct 8, 2026
- Labelled
- 1 mg
- Measured
- 1.01 mg

| Test | Method | Limit | Result |
|---|---|---|---|
| Purity | HPLC | ≥ 99.0% | 99.40% |
| Identity | Mass spectrometry | 9117.6 ± 1.0 Da | 9117.5 Da |
| Net content | Quantitative HPLC | ≥ 1 mg | 1.01 mg |
| Endotoxin | LAL assay | ≤ 0.5 EU/mg | 0.07 EU/mg |
| Sterility | Membrane filtration | No growth | No growth |
| Heavy metals | ICP-MS | ≤ 10 ppm total | 0.6 ppm |
| Moisture | Karl Fischer | ≤ 8.0% | 3.9% |
83-residue IGF-1 analog
C400H625N111O115S9
9117.6 Da · 83 residues
83-residue chain. The full sequence and its mass-spec confirmation are on each lot certificate.
Endocrine · 83-residue IGF-1 analog
1 mg · 83 residues · 9117.6 Da
Size$95.00/mg
Quantity10+ of one compound: 40% off
Same-day dispatch on orders by 2 PM ET, Monday to Friday
Arrives in 2 business days, tracked
Free shipping over $150
For in-vitro research use only. Not for human or animal use.
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Semax 10 mg01Verified test results
IGF-1 LR3 lot SA-IGF-2610 was tested Oct 8, 2026 at an independent laboratory before it shipped. Every value is printed against its limit, so a pass means something.
Certificate of analysis
99.40%
Purity by HPLC
Profile drawn from the reported purity
Purity by HPLC, identity by mass spectrometry, net content by quantitative HPLC, endotoxin by LAL, sterility by membrane filtration, heavy metals by ICP-MS and moisture by Karl Fischer. Report SA-IGF-2610-01, Oct 8, 2026. Open the lot record.
Open any lot's certificate. Your order ships from the current released lot, and its QR code opens this record.

99.40%
HPLC purity
Tested Oct 8, 2026 · 7/7 assays · sample

99.80%
HPLC purity
Tested Sep 10, 2026 · 7/7 assays · sample
02Verify your vial
Every vial label carries a QR code. Point your phone camera at it.
The code opens that lot's certificate with every assay value. No phone? Type the lot from your packing slip on Verify a lot.
Each signed certificate links to the lab's own verification page, so the report can be confirmed independently of us.
03Analytical identity
Studied as a serum-free cell-culture supplement and in IGF-1 receptor models in vitro.
| Compound | 83-residue IGF-1 analog |
|---|---|
| Formula | C400H625N111O115S9 |
| Molecular weight | 9117.6 Da |
| Residues | 83 |
| CAS | 946870-92-4 |
| Form | Lyophilised powder, 1 mg |
| Storage | Sealed at -20 °C, away from light and moisture |
Sequence
83-residue chain. The full sequence and its mass-spec confirmation are on each lot certificate.
04In the lab
IGF-1 LR3 is IGF-I with Arg in place of Glu3 plus a 13-residue N-terminal extension, and it binds IGF-binding proteins at least 1000-fold more weakly. In laboratory research it raised Akt signaling in mammary tissue and nitric-oxide-dependent artery responses.

Compound
IGF-1 LR3Arg3 IGF-I with a 13-residue N-terminal extensionMammary arteries
Endpoint studied
Shifted noradrenaline constriction in isolated arteries; lost without endothelium or with NOS blocked.
Gow 2000 · PMID 10825414Mammary tissue
Endpoint studied
Raised phospho-Akt and SOCS3 gene expression in mammary tissue, with a modest rise in lactation capacity.
Hadsell 2008 · PMID 18577570Preimplantation embryos
Endpoint studied
Most cells per blastocyst; IGF-I-R mRNA rose 1.3-fold and IGFBP-2 mRNA 2.8-fold vs control.
Prelle 2001 · PMID 11181549Pathways as reported in the cited laboratory studies. For in-vitro research use only.
05Research history
5 milestones, each linked to its PubMed record
The Journal of Endocrinology
LR3IGF-I, a potent analog with markedly reduced IGFBP binding, circulates mostly as free peptide and clears faster than IGF-I.
PubMed · PMID 7693845The American Journal of Physiology
Enlarged gut, kidney and spleen in a developing gut model; LR3IGF-I was more potent than IGF-I.
PubMed · PMID 9124573The Journal of Biological Chemistry
Mass spectrometry traps three disulfide folding intermediates of LR3IGF-I, which carries Arg3 and a 13-residue extension.
PubMed · PMID 10608814Experimental Physiology
Isolated mammary arteries constrict less to noradrenaline, an effect that needs endothelium and nitric oxide synthesis.
PubMed · PMID 10825414Journal of Alzheimer's Disease
Shifted cortical plaques toward inert forms in an amyloid model but did not preserve memory.
PubMed · PMID 39610283 LatestLaboratory research only, cited for research context. Not a claim about use in people.
06Questions
About IGF-1 LR3, its certificate and your order.
Email [email protected], Monday to Friday. A person replies within one business day.
The current released lot, SA-IGF-2610. Scan the QR code on the vial label to open its certificate. The lot number is also on your packing slip, and the full certificate is here.
Every certificate is issued by an independent laboratory. Each lot has its own public record page with every assay value, and a link to verify the report on the lab's own site once the signed PDF is posted.
Vials are filled slightly over the labelled mass so that every vial meets it. Net content is measured on each lot and published as a number, not a pass.
Email [email protected] within 7 days with your order number and a photo and we will replace it.
Orders by 2 PM ET on a weekday ship the same day, with tracking emailed when the label prints.
No. It is sold strictly for in-vitro laboratory research and is not for human or animal use of any kind.
07Complete the box
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