| Test | Method | Limit | Result |
|---|---|---|---|
| Purity | HPLC | ≥ 99.0% | 99.71% |
| Identity | Mass spectrometry | Each component | All confirmed |
| Net content | Quantitative HPLC | ≥ 50 mg | 50.63 mg |
| Endotoxin | LAL assay | ≤ 0.5 EU/mg | 0.12 EU/mg |
| Sterility | Membrane filtration | No growth | No growth |
| Heavy metals | ICP-MS | ≤ 10 ppm total | 1.1 ppm |
| Moisture | Karl Fischer | ≤ 8.0% | 3.6% |
Adenosine analog studied as an AMPK pathway activator
On each lot certificate
Small molecule
A small molecule, not a peptide chain. Its structure is confirmed by mass spectrometry on every lot certificate.
Cellular · Adenosine analog studied as an AMPK pathway activator
50 mg · Small molecule
Size$1.40/mg
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For in-vitro research use only. Not for human or animal use.
Cellular
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GLP-3 RT 5 mg01Verified test results
AICAR lot SA-AIC-2610 was tested Oct 8, 2026 at an independent laboratory before it shipped. Every value is printed against its limit, so a pass means something.
Certificate of analysis
99.71%
Purity by HPLC
Profile drawn from the reported purity
Purity by HPLC, identity by mass spectrometry, net content by quantitative HPLC, endotoxin by LAL, sterility by membrane filtration, heavy metals by ICP-MS and moisture by Karl Fischer. Report SA-AIC-2610-01, Oct 8, 2026. Open the lot record.
Open any lot's certificate. Your order ships from the current released lot, and its QR code opens this record.
99.71%
HPLC purity
Tested Oct 8, 2026 · 7/7 assays · sample
99.55%
HPLC purity
Tested Sep 10, 2026 · 7/7 assays · sample
02Verify your vial
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03Analytical identity
Studied in mitochondrial function and cellular-energy models in vitro.
| Compound | Adenosine analog studied as an AMPK pathway activator |
|---|---|
| Formula | On each lot certificate |
| Molecular weight | On each lot certificate |
| Type | Small molecule |
| Form | Powder, 50 mg |
| Storage | Sealed at -20 °C, away from light and moisture |
Structure
A small molecule, not a peptide chain. Its structure is confirmed by mass spectrometry on every lot certificate.
04In the lab
AICAR is a nucleoside that cells convert to ZMP, an AMP mimic that activates AMP-activated protein kinase (AMPK). In hepatocytes it nearly stopped fatty acid and sterol synthesis, and in perfused muscle it raised fatty acid oxidation and glucose uptake.
Compound
AICARAdenosine analog that cells convert to ZMP, an AMP mimicHepatocytes
Endpoint studied
ZMP built up without shifting ATP, ADP or AMP; AMPK was activated and HMG-CoA reductase inactivated.
Corton 1995 · PMID 7744080Perfused hindlimb muscle
Endpoint studied
AMPK rose, ACC was inactivated and malonyl-CoA fell; glucose uptake rose while oxygen uptake did not change.
Merrill 1997 · PMID 9435525Perfused hindlimb muscle
Endpoint studied
Glucose uptake rose as GLUT4 moved to the surface membrane, as with contraction.
Kurth-Kraczek 1999 · PMID 10426389Pathways as reported in the cited laboratory studies. For in-vitro research use only.
05Research history
5 milestones, each linked to its PubMed record
European Journal of Biochemistry
In hepatocytes AICAR forms ZMP, activates AMPK without shifting ATP, ADP or AMP, and shuts down fatty acid and sterol synthesis.
PubMed · PMID 7744080FASEB Journal
In hepatocyte suspensions AICAR inactivated acetyl-CoA carboxylase and HMG-CoA reductase, cutting fatty acid and cholesterol synthesis.
PubMed · PMID 7737463The American Journal of Physiology
In perfused hindlimb muscle AICAR activated AMPK, lowered malonyl-CoA and raised fatty acid oxidation 2.8-fold, plus glucose uptake.
PubMed · PMID 9435525Diabetes
AMPK activation by AICAR raised glucose uptake in perfused muscle through GLUT4 translocation to the surface membrane.
PubMed · PMID 10426389Cell
Four weeks of AICAR in a sedentary laboratory model switched on muscle metabolic genes and raised running endurance by 44%.
PubMed · PMID 18674809 LatestLaboratory research only, cited for research context. Not a claim about use in people.
06Questions
About AICAR, its certificate and your order.
Email [email protected], Monday to Friday. A person replies within one business day.
The current released lot, SA-AIC-2610. Scan the QR code on the vial label to open its certificate. The lot number is also on your packing slip, and the full certificate is here.
Every certificate is issued by an independent laboratory. Each lot has its own public record page with every assay value, and a link to verify the report on the lab's own site once the signed PDF is posted.
Vials are filled slightly over the labelled mass so that every vial meets it. Net content is measured on each lot and published as a number, not a pass.
Email [email protected] within 7 days with your order number and a photo and we will replace it.
Orders by 2 PM ET on a weekday ship the same day, with tracking emailed when the label prints.
No. It is sold strictly for in-vitro laboratory research and is not for human or animal use of any kind.
07Complete the box
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