| Test | Method | Limit | Result |
|---|---|---|---|
| Purity | HPLC | ≥ 99.0% | 99.20% |
| Identity | Mass spectrometry | 390.4 ± 1.0 Da | 390.2 Da |
| Net content | Quantitative HPLC | ≥ 50 mg | 51.00 mg |
| Endotoxin | LAL assay | ≤ 0.5 EU/mg | 0.07 EU/mg |
| Sterility | Membrane filtration | No growth | No growth |
| Heavy metals | ICP-MS | ≤ 10 ppm total | 0.5 ppm |
| Moisture | Karl Fischer | ≤ 8.0% | 2.5% |
Synthetic tetrapeptide
C14H22N4O9
390.35 Da · 4 residues
Cellular · Synthetic tetrapeptide
50 mg · 4 residues · 390.35 Da
Size$1.70/mg
Quantity10+ of one compound: 40% off
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For in-vitro research use only. Not for human or animal use.
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GLP-3 RT 5 mg01Verified test results
Epithalon lot SA-EPI-2610 was tested Oct 8, 2026 at an independent laboratory before it shipped. Every value is printed against its limit, so a pass means something.
Certificate of analysis
99.20%
Purity by HPLC
Profile drawn from the reported purity
Purity by HPLC, identity by mass spectrometry, net content by quantitative HPLC, endotoxin by LAL, sterility by membrane filtration, heavy metals by ICP-MS and moisture by Karl Fischer. Report SA-EPI-2610-01, Oct 8, 2026. Open the lot record.
Open any lot's certificate. Your order ships from the current released lot, and its QR code opens this record.
99.20%
HPLC purity
Tested Oct 8, 2026 · 7/7 assays · sample
99.62%
HPLC purity
Tested Sep 10, 2026 · 7/7 assays · sample
02Verify your vial
Every vial label carries a QR code. Point your phone camera at it.
The code opens that lot's certificate with every assay value. No phone? Type the lot from your packing slip on Verify a lot.
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03Analytical identity
Studied in telomerase and cellular-ageing models in vitro.
| Compound | Synthetic tetrapeptide |
|---|---|
| Formula | C14H22N4O9 |
| Molecular weight | 390.35 Da |
| Residues | 4 |
| CAS | 307297-39-8 |
| Form | Lyophilised powder, 50 mg |
| Storage | Sealed at -20 °C, away from light and moisture |
Sequence
Side-chain composition
Every heavy atom is placed from the sequence with ideal bond lengths and angles, so the connectivity is exact. The pose is idealised (an extended chain) and is not a measured conformation. Identity for each lot is confirmed on its certificate.
Structure viewer04In the lab
Epithalon is the synthetic tetrapeptide Ala-Glu-Asp-Gly. In cultured human cells it raised hTERT expression and telomerase activity with telomere lengthening, and molecular modeling suggests it may bind H1 histones.
Compound
EpithalonSynthetic tetrapeptide Ala-Glu-Asp-Gly (AEDG)Normal human cell lines
Endpoint studied
Telomeres lengthened with concentration, with more hTERT mRNA and telomerase; cancer lines used ALT.
Al-Dulaimi 2025 · PMID 40908429Gingival stem cells
Endpoint studied
Nestin, GAP43, beta III tubulin and doublecortin mRNA rose 1.6 to 1.8-fold; modeling showed H1 binding.
Khavinson 2020 · PMID 32019204Aging oocytes in culture
Endpoint studied
Lower ROS, fewer spindle defects, higher mitochondrial membrane potential and mtDNA copy number.
Yue 2022 · PMID 35413689Pathways as reported in the cited laboratory studies. For in-vitro research use only.
05Research history
5 milestones, each linked to its PubMed record
Mechanisms of Ageing and Development
Effects of the synthetic tetrapeptide Ala-Glu-Asp-Gly are reported in a lifespan model.
PubMed · PMID 11087911Bulletin of Experimental Biology and Medicine
Telomerase-negative human fetal fibroblasts expressed its catalytic subunit, gained activity and lengthened telomeres.
PubMed · PMID 12937682Molecules
Neuronal differentiation markers rose in human gingival stem cells; modeling showed binding to H1 histones.
PubMed · PMID 32019204Aging
Lower ROS and higher mitochondrial membrane potential delayed in vitro aging and apoptosis of oocytes.
PubMed · PMID 35413689Biogerontology
Normal human cells lengthened telomeres via hTERT and telomerase; cancer cell lines used ALT.
PubMed · PMID 40908429 LatestLaboratory research only, cited for research context. Not a claim about use in people.
06Questions
About Epithalon, its certificate and your order.
Email [email protected], Monday to Friday. A person replies within one business day.
The current released lot, SA-EPI-2610. Scan the QR code on the vial label to open its certificate. The lot number is also on your packing slip, and the full certificate is here.
Every certificate is issued by an independent laboratory. Each lot has its own public record page with every assay value, and a link to verify the report on the lab's own site once the signed PDF is posted.
Vials are filled slightly over the labelled mass so that every vial meets it. Net content is measured on each lot and published as a number, not a pass.
Email [email protected] within 7 days with your order number and a photo and we will replace it.
Orders by 2 PM ET on a weekday ship the same day, with tracking emailed when the label prints.
No. It is sold strictly for in-vitro laboratory research and is not for human or animal use of any kind.
07Complete the box
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