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Cellular · Mitochondrial-derived peptide + pyridine dinucleotide coenzyme (10 mg + 100 mg)

MOTS-c / NAD+

10 / 100 mg · 2-compound blend

$95.00per vial

Size$0.86/mg

10 / 100 mg Lyophilised · sealed vial

Quantity10+ of one compound: 40% off

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  • 7 tests, every lotIndependent lab
  • 2 Day ShippingFrom the USA, tracked
  • Encrypted checkoutSSL secured
  • PassedSterility & endotoxin
  • PassedIdentity & purity, 99.15%

For in-vitro research use only. Not for human or animal use.

Researchers also add

01Verified test results

Every lot, independently tested.

MOTS-c / NAD+ lot SA-MO1-2610 was tested Oct 8, 2026 at an independent laboratory before it shipped. Every value is printed against its limit, so a pass means something.

Independent labIndependent third-party laboratorySample data

Certificate of analysis

99.15%

Purity by HPLC

Profile drawn from the reported purity

Lot
SA-MO1-2610
Tested
Oct 8, 2026
Labelled
110 mg
Measured
111.13 mg
7 of 7 within limitsQR on every label
Full release panel7 passed · 0 flagged
  • PurityHPLC · limit ≥ 99.0%99.15%Pass
  • IdentityMass spectrometry · limit Each componentAll confirmedPass
  • Net contentQuantitative HPLC · limit ≥ 110 mg111.13 mgPass
  • EndotoxinLAL assay · limit ≤ 0.5 EU/mg0.11 EU/mgPass
  • SterilityMembrane filtration · limit No growthNo growthPass
  • Heavy metalsICP-MS · limit ≤ 10 ppm total0.4 ppmPass
  • MoistureKarl Fischer · limit ≤ 8.0%3.8%Pass

Purity by HPLC, identity by mass spectrometry, net content by quantitative HPLC, endotoxin by LAL, sterility by membrane filtration, heavy metals by ICP-MS and moisture by Karl Fischer. Report SA-MO1-2610-01, Oct 8, 2026. Open the lot record.

Every lot on record

Open any lot's certificate. Your order ships from the current released lot, and its QR code opens this record.

All 2 MOTS-c / NAD+ lots
Latest
MOTS-c / NAD+ 10 / 100 mgLot SA-MO1-2610

99.15%

HPLC purity

Labelled110 mgMeasured111.13 mg+1.0%
  • IdentityConfirmed
  • EndotoxinPass
  • SterilityNo growth
  • Heavy metalsPass

Tested Oct 8, 2026 · 7/7 assays · sample

MOTS-c / NAD+ 10 / 100 mgLot SA-MO1-2609

99.42%

HPLC purity

Labelled110 mgMeasured112.91 mg+2.6%
  • IdentityConfirmed
  • EndotoxinPass
  • SterilityNo growth
  • Heavy metalsPass

Tested Sep 10, 2026 · 7/7 assays · sample

02Verify your vial

Three steps from label to lab.

  1. 01Scan the label

    Every vial label carries a QR code. Point your phone camera at it.

  2. 02Land on its record

    The code opens that lot's certificate with every assay value. No phone? Type the lot from your packing slip on Verify a lot.

  3. 03Check it with the lab

    Each signed certificate links to the lab's own verification page, so the report can be confirmed independently of us.

03Analytical identity

MOTS-c / NAD+, molecule by molecule.

Studied in mitochondrial function and cellular-energy models in vitro.

CompoundMitochondrial-derived peptide + pyridine dinucleotide coenzyme (10 mg + 100 mg)
FormulaPer component
Molecular weightPer component
Type2 compounds
FormLyophilised powder, 10 / 100 mg
StorageSealed at -20 °C, away from light and moisture

Components

  • MOTS-c10 mg
  • NAD+100 mg

Each component is confirmed separately on the lot certificate.

04In the lab

How MOTS-c / NAD+ is studied to work.

MOTS-c and NAD+ are each studied on their own pathways in laboratory research. This blend combines them in one vial; the map shows the best-characterized pathway reported for each.

Blend

MOTS-c / NAD+Blend of MOTS-c and NAD+
  1. MOTS-c

    Metabolic signaling

    • Folate cycle
    • Purine synth.
    • AMPK

    Endpoint studied

    Insulin sensitivity

    Inhibited the folate cycle and de novo purine synthesis, leading to AMPK activation.

    Lee 2015 · PMID 25738459
  2. NAD+

    Sirtuin deacetylation

    • NAD
    • Sir2
    • Histone H4K16

    Endpoint studied

    Gene silencing

    Sir2 proteins are NAD-dependent deacetylases of histone H3 lysines 9 and 14 and H4 lysine 16.

    Imai 2000 · PMID 10693811

Pathways as reported in the cited laboratory studies, for each compound in the blend. For in-vitro research use only.

05Research history

18 years in the literature.

5 milestones, each linked to its PubMed record

  1. 2000

    NAD+ · Nature

    Sirtuins need NAD

    Sir2 is shown to be an NAD-dependent histone deacetylase, linking metabolism to gene silencing.

    PubMed · PMID 10693811
  2. 2003

    NAD+ · Biochemical and Biophysical Research Communications

    NAD+ repletion in astrocytes

    Restoring NAD+ after PARP-1 activation restored glycolysis and prevented death in cultured astrocytes.

    PubMed · PMID 12927790
  3. 2015

    MOTS-c · Cell Metabolism

    MOTS-c is discovered

    A 16-amino-acid peptide encoded in the mitochondrial 12S rRNA is reported, acting on the folate cycle and AMPK.

    PubMed · PMID 25738459
  4. 2016

    MOTS-c · Biochemical and Biophysical Research Communications

    A bone loss model

    Less bone loss in a bone loss model, with RANKL-induced osteoclast formation inhibited partly through AMPK.

    PubMed · PMID 27237975
  5. 2018

    MOTS-c · Cell Metabolism

    It enters the nucleus

    Under metabolic stress MOTS-c moves to the nucleus, AMPK-dependent, regulating ARE genes and interacting with NRF2.

    PubMed · PMID 29983246 Latest

Laboratory research only, cited for research context. Not a claim about use in people.

06Questions

Frequently asked questions.

About MOTS-c / NAD+, its certificate and your order.

Need assistance? We’re here to help.

Email [email protected], Monday to Friday. A person replies within one business day.

01Which lot will I receive?

The current released lot, SA-MO1-2610. Scan the QR code on the vial label to open its certificate. The lot number is also on your packing slip, and the full certificate is here.

02Is the certificate real, and can I check it?

Every certificate is issued by an independent laboratory. Each lot has its own public record page with every assay value, and a link to verify the report on the lab's own site once the signed PDF is posted.

03Why does net content show more than 110 mg?

Vials are filled slightly over the labelled mass so that every vial meets it. Net content is measured on each lot and published as a number, not a pass.

04What if the vial arrives without vacuum or damaged?

Email [email protected] within 7 days with your order number and a photo and we will replace it.

05When will it ship?

Orders by 2 PM ET on a weekday ship the same day, with tracking emailed when the label prints.

06Is MOTS-c / NAD+ for human use?

No. It is sold strictly for in-vitro laboratory research and is not for human or animal use of any kind.

07Complete the box

Every vial counts toward your price.

3+ vials 25% off and 5+ vials 30% off across any mix, 10+ of one compound 40% off, 50+ of one compound 50% off.

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MOTS-c / NAD+10 / 100 mg · $95.00
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